Healing peptides

BPC-157 vs TB-500

Comparing BPC-157 and TB-500 across evidence, dosing, mechanisms, and research areas.

vs
Category
healingrecovery
healingrecovery
Molecular weight
1419.53 g/mol
4963.44 g/mol
Half-life
~4 hours (stable in gastric juice — unique among peptides)
~14 days
Admin routes
subcutaneousintramuscularoraltopical
subcutaneousintramusculartopical
Research areas
Tendon/ligament repairGut healing (IBD, ulcers, leaky gut)Muscle injury recoveryNeuroprotectionBone fracture healingWound healingOrgan protection (liver, pancreas, heart)
Tissue repairCardiac repairWound healingHair regrowthAnti-inflammationRenal protectionCorneal repair
Typical dosing
250–500 mcg · 1-2x daily · 4-12 weeks
2000–5000 mcg · 2x weekly · 4-8 weeks loading, 4 weeks maintenance
FDA status
Not FDA-approved and NOT compoundable as of June 2026 (per regulatory-status-refresh-2026-06): removed from the Category 2 do-not-compound list in April 2026 (nomination withdrawn, effective 2026-04-23) — this is a procedural step, not approval, and BPC-157 is NOT Category 1. PCAC review scheduled Jul 23, 2026. Also WADA-prohibited (S0).
Not FDA-approved. FDA Category 2 (under evaluation for compounding)
WADA status
Prohibited (S0 category — non-approved substances, effective January 2022)
Prohibited (S0 — non-approved substances, effective 2011)
PubMed studies
213
1,039