Stack · Promising

HPTA Reboot Stack Dosage Guide

Kisspeptin-10 + Gonadotropin + CJC-1295 + Ipamorelin

Kickstart hypothalamus-pituitary-testicular axis

Last updated · 2026-04-27
Male Hormonal Health aka Kisspeptin-10 + Gonadotropin + CJC-1295 / Ipamorelin aka HPTA restart stack aka post-cycle therapy peptide stack
Promising

Reasonable pairing with mechanistic rationale; widely used in community protocols.

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Components

Kisspeptin

Endogenous ligand for GPR54 (KISS1R). Activates hypothalamic GnRH neurons, triggering pulsatile GnRH release and downstream LH/FSH secretion. Master regulator of reproductive axis initiation and maintenance.

Half-life: KP-54: ~28 minutes (IV); KP-10: ~4 minutes (IV)

Gonadotropin

Compound page not yet published

CJC-1295 + Ipamorelin

Compound page not yet published

Kickstart hypothalamus-pituitary-testicular axis