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hormone

GHRP-2

FDA: research-only

GHRP-2 is a ghrelin mimetic growth hormone releasing peptide that stimulates GH release via the ghrelin receptor (GHS-R1a). It promotes muscle growth, fat metabolism, and recovery, and is known for its appetite-increasing effects. Ghrelin mimetic that stimulates the release of growth hormone via the ghrelin receptor (GHS-R1a). Promotes muscle growth, fat metabolism, and recovery. Known to increase hunger via ghrelin pathway activation. Often paired with GHRH analogs for synergistic GH release. - Growth hormone stimulation - Muscle growth and recovery - Fat metabolism enhancement - Appetite stimulation (useful in muscle-wasting scenarios) - Recovery support - Standard: 100-300 mcg SubQ 2-3x/day

This content is for educational and research purposes only. VialBase does not provide medical advice. Consult a healthcare professional before using any peptide.

Molecular weight —
Half-life —
CAS number 158861-67-7
Route —
02

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5mg

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Stocks this compound Third-party tested Public COAs

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What bloodwork do I need?

Reference ranges are general guidelines. Consult your physician for interpretation.

PRE-CYCLE
  • IGF-1
  • Fasting Glucose
  • Fasting Insulin
  • Cortisol (AM)
  • Prolactin
  • CMP
  • CBC
DURING CYCLE
  • IGF-1
  • Cortisol (AM)
  • Prolactin
  • Fasting Glucose
POST-CYCLE
  • IGF-1
  • Cortisol (AM)
  • Prolactin
  • Fasting Glucose
Safety & Regulatory Status
FDA STATUS research-only

Regulatory status for GHRP-2 may change. Verify current status with your jurisdiction before use. This is not legal or medical advice.

Frequently Asked Questions

What is GHRP-2?
GHRP-2 (growth hormone releasing peptide 2) is a synthetic ghrelin-mimetic secretagogue that stimulates the body's own growth hormone release through the ghrelin receptor (GHS-R1a). It is studied for muscle growth, fat metabolism, and recovery, and is known to increase appetite. It is a research-only compound and is not FDA-approved.
How does GHRP-2 work?
GHRP-2 mimics ghrelin and binds the growth hormone secretagogue receptor (GHS-R1a) on the pituitary, triggering a pulse of endogenous growth hormone. Activating the ghrelin pathway also increases hunger. It is frequently paired with a GHRH analog such as CJC-1295, because combining a GHRH analog with a GHRP produces a larger, synergistic GH pulse than either alone.
How is GHRP-2 dosed?
Commonly cited research protocols use 100–300 mcg subcutaneously, two to three times daily, and it is often timed alongside a GHRH analog for synergistic growth-hormone release. Administration is by subcutaneous injection. These figures reflect research protocols, not medical advice — consult a clinician before use.
What are the benefits and evidence for GHRP-2?
The evidence tier is mechanistic and preclinical, not large human outcome trials. As a ghrelin-receptor agonist, GHRP-2 is studied for raising endogenous growth hormone, supporting muscle growth and recovery, aiding fat metabolism, and stimulating appetite in muscle-wasting scenarios. Because robust human trial data are limited, these are research-context benefits rather than proven clinical outcomes.
What are the side effects of GHRP-2?
Reported effects include flushing, tingling, and water retention. GHRP-2 may elevate cortisol and prolactin more than the more selective Ipamorelin, so monitoring is advised with long-term use, and effects depend on pituitary function. It stimulates appetite, though generally less than GHRP-6. It is considered to act more physiologically than direct HGH injection.
How does GHRP-2 compare to Ipamorelin and GHRP-6?
All three raise endogenous growth hormone through the ghrelin receptor. GHRP-2 has a moderate appetite effect and can raise cortisol and prolactin. GHRP-6 is the strongest appetite stimulant. Ipamorelin is the most selective, with little effect on cortisol, prolactin, or hunger. GHRP-2 can substitute for Ipamorelin in GH stacks when a stronger ghrelin effect is acceptable.
Is GHRP-2 FDA-approved?
No. GHRP-2 is a research-only compound and is not FDA-approved for human use. It is available through research-chemical suppliers and is banned in competitive sports. Because it is unapproved, purity and dosing accuracy are not guaranteed, and it should not be regarded as a clinician-validated treatment.