.stack-dosing[data-astro-cid-p7tig5yi]{margin:0}.title[data-astro-cid-p7tig5yi]{font-size:1rem;font-weight:600;margin:0 0 .75rem;color:var(--slate-200)}.table-wrap[data-astro-cid-p7tig5yi]{overflow-x:auto}.dosing-table[data-astro-cid-p7tig5yi]{width:100%;font-size:.875rem;border-collapse:collapse}.dosing-table[data-astro-cid-p7tig5yi] thead[data-astro-cid-p7tig5yi] tr[data-astro-cid-p7tig5yi]{border-bottom:1px solid var(--navy-700);text-align:left;color:var(--slate-400)}.dosing-table[data-astro-cid-p7tig5yi] th[data-astro-cid-p7tig5yi]{padding:.5rem 1rem .5rem 0;font-weight:500}.dosing-table[data-astro-cid-p7tig5yi] tbody[data-astro-cid-p7tig5yi] tr[data-astro-cid-p7tig5yi]{border-bottom:1px solid var(--navy-800)}.dosing-table[data-astro-cid-p7tig5yi] tbody[data-astro-cid-p7tig5yi] tr[data-astro-cid-p7tig5yi]:last-child{border-bottom:none}.dosing-table[data-astro-cid-p7tig5yi] td[data-astro-cid-p7tig5yi]{padding:.5rem 1rem .5rem 0;color:var(--slate-200)}.dosing-table[data-astro-cid-p7tig5yi] .compound[data-astro-cid-p7tig5yi]{font-weight:500}.cycle[data-astro-cid-p7tig5yi]{margin:.75rem 0 0;font-size:.875rem;color:var(--slate-300)}.cycle[data-astro-cid-p7tig5yi] strong[data-astro-cid-p7tig5yi]{color:var(--slate-200)}.components-grid[data-astro-cid-gtoxc47g]{display:grid;grid-template-columns:repeat(1,1fr);gap:.75rem}@media(min-width:640px){.components-grid[data-astro-cid-gtoxc47g]{grid-template-columns:repeat(2,1fr)}}@media(min-width:1024px){.components-grid[data-astro-cid-gtoxc47g]{grid-template-columns:repeat(3,1fr)}}.component-card[data-astro-cid-gtoxc47g]{display:block;padding:1rem;border:1px solid var(--navy-700);border-radius:var(--r-card);background:var(--navy-900);text-decoration:none;transition:border-color .15s ease}.component-card[data-astro-cid-gtoxc47g]:hover{border-color:var(--cobalt-500, #3b82f6)}.component-card[data-astro-cid-gtoxc47g].unpublished{opacity:.6}.component-name[data-astro-cid-gtoxc47g]{font-weight:500;color:var(--slate-100);margin:0 0 .25rem}.component-mechanism[data-astro-cid-gtoxc47g]{font-size:.875rem;color:var(--slate-300);margin:.25rem 0;display:-webkit-box;-webkit-line-clamp:2;-webkit-box-orient:vertical;overflow:hidden}.component-meta[data-astro-cid-gtoxc47g]{font-size:.75rem;color:var(--slate-400);margin:.5rem 0 0}.stk-wrap[data-astro-cid-fs2v3uau]{max-width:1000px;margin:0 auto;padding:40px 28px 120px}@media(max-width:640px){.stk-wrap[data-astro-cid-fs2v3uau]{padding:24px 16px 80px}}.stk-crumbs[data-astro-cid-fs2v3uau]{font-family:var(--f-mono);font-size:11px;color:var(--slate-500);letter-spacing:.12em;text-transform:uppercase;margin-bottom:24px}.stk-crumbs[data-astro-cid-fs2v3uau] a[data-astro-cid-fs2v3uau]{color:var(--slate-500);text-decoration:none;transition:color .15s}.stk-crumbs[data-astro-cid-fs2v3uau] a[data-astro-cid-fs2v3uau]:hover{color:var(--accent)}.stk-crumbs[data-astro-cid-fs2v3uau] .sep[data-astro-cid-fs2v3uau]{color:var(--slate-600);margin:0 8px}.stk-crumbs[data-astro-cid-fs2v3uau] .current[data-astro-cid-fs2v3uau]{color:var(--slate-200)}.stk-header[data-astro-cid-fs2v3uau]{margin-bottom:28px;padding-bottom:28px;border-bottom:1px solid var(--navy-700)}.stk-eyebrow[data-astro-cid-fs2v3uau]{font-family:var(--f-mono);font-size:11px;color:var(--slate-500);letter-spacing:.14em;text-transform:uppercase;margin-bottom:14px}.stk-title[data-astro-cid-fs2v3uau]{font-family:var(--f-display);font-size:clamp(36px,5.5vw,64px);font-weight:500;letter-spacing:-.035em;line-height:1.05;margin:0 0 18px;color:var(--slate-100)}.stk-title[data-astro-cid-fs2v3uau] .plus[data-astro-cid-fs2v3uau]{color:var(--slate-600);font-weight:400}.stk-dek[data-astro-cid-fs2v3uau]{font-family:var(--f-body);font-size:18px;color:var(--slate-300);line-height:1.55;max-width:62ch;margin:0 0 16px}.stk-updated[data-astro-cid-fs2v3uau]{font-family:var(--f-mono);font-size:11px;color:var(--slate-500);letter-spacing:.08em;text-transform:uppercase}.stk-banner[data-astro-cid-fs2v3uau]{display:flex;align-items:center;gap:14px;margin-bottom:32px;padding:18px 22px;background:var(--navy-900);border:1px solid var(--navy-700);border-left:3px solid #6b7280;border-radius:var(--r-md)}.stk-banner[data-astro-cid-fs2v3uau] p[data-astro-cid-fs2v3uau]{margin:0;font-size:14px;color:var(--slate-300);line-height:1.55}.stk-mech-grid[data-astro-cid-fs2v3uau]{display:grid;grid-template-columns:repeat(auto-fit,minmax(300px,1fr));gap:12px;margin-bottom:40px}.stk-mech-card[data-astro-cid-fs2v3uau]{background:var(--navy-900);border:1px solid var(--navy-700);border-radius:var(--r-md);padding:20px}.stk-mech-head[data-astro-cid-fs2v3uau]{display:flex;justify-content:space-between;align-items:baseline;gap:12px;margin-bottom:10px}.stk-mech-name[data-astro-cid-fs2v3uau]{font-family:var(--f-display);font-size:17px;font-weight:600;letter-spacing:-.015em}.stk-mech-name[data-astro-cid-fs2v3uau] a[data-astro-cid-fs2v3uau]{color:var(--slate-100);text-decoration:none;border-bottom:1px solid transparent;transition:border-color .15s,color .15s}.stk-mech-name[data-astro-cid-fs2v3uau] a[data-astro-cid-fs2v3uau]:hover{color:var(--accent);border-bottom-color:var(--accent)}.stk-mech-cat[data-astro-cid-fs2v3uau]{font-family:var(--f-mono);font-size:10px;letter-spacing:.14em;text-transform:uppercase;color:var(--slate-500)}.stk-mech-card[data-astro-cid-fs2v3uau] p[data-astro-cid-fs2v3uau]{font-size:13.5px;color:var(--slate-400);line-height:1.6;margin:0}.stk-body[data-astro-cid-fs2v3uau] h1{display:none}.stk-body[data-astro-cid-fs2v3uau] h2{font-family:var(--f-display);font-size:22px;font-weight:600;letter-spacing:-.02em;color:var(--slate-100);margin:40px 0 14px;padding-bottom:10px;border-bottom:1px solid var(--navy-800);scroll-margin-top:80px}.stk-body[data-astro-cid-fs2v3uau] h3{font-family:var(--f-display);font-size:17px;font-weight:600;color:var(--slate-100);letter-spacing:-.015em;margin:28px 0 12px}.stk-body[data-astro-cid-fs2v3uau] p{font-family:var(--f-body);font-size:15.5px;color:var(--slate-300);line-height:1.7;margin:0 0 16px}.stk-body[data-astro-cid-fs2v3uau] ul,.stk-body[data-astro-cid-fs2v3uau] ol{font-size:15.5px;color:var(--slate-300);line-height:1.7;margin:0 0 16px;padding-left:24px}.stk-body[data-astro-cid-fs2v3uau] li{margin-bottom:6px}.stk-body[data-astro-cid-fs2v3uau] strong{color:var(--slate-100);font-weight:600}.stk-body[data-astro-cid-fs2v3uau] a{color:var(--accent);text-decoration:none;border-bottom:1px solid rgba(59,130,246,.35)}.stk-body[data-astro-cid-fs2v3uau] a:hover{color:var(--accent-bright);border-bottom-color:var(--accent)}.stk-body[data-astro-cid-fs2v3uau] table{width:100%;border-collapse:collapse;margin:18px 0 24px;background:var(--navy-900);border:1px solid var(--navy-700);border-radius:var(--r-md);overflow:hidden}.stk-body[data-astro-cid-fs2v3uau] thead{background:var(--navy-950)}.stk-body[data-astro-cid-fs2v3uau] th{font-family:var(--f-mono);font-size:10.5px;letter-spacing:.12em;text-transform:uppercase;color:var(--slate-500);padding:12px 14px;text-align:left;border-bottom:1px solid var(--navy-700)}.stk-body[data-astro-cid-fs2v3uau] td{font-size:13.5px;color:var(--slate-200);padding:12px 14px;border-bottom:1px solid var(--navy-800);line-height:1.5}.stk-body[data-astro-cid-fs2v3uau] tr:last-child td{border-bottom:none}.stk-body[data-astro-cid-fs2v3uau] code{font-family:var(--f-mono);font-size:13px;background:var(--navy-800);border:1px solid var(--navy-700);padding:1px 6px;border-radius:4px;color:var(--slate-200)}.stk-body[data-astro-cid-fs2v3uau] blockquote{border-left:2px solid var(--accent);padding:2px 0 2px 20px;margin:20px 0;color:var(--slate-300);font-size:15px;line-height:1.7}.stk-disclaimer[data-astro-cid-fs2v3uau]{margin-top:56px;padding-top:24px;border-top:1px solid var(--navy-700);font-family:var(--f-body);font-size:12.5px;font-style:italic;color:var(--slate-500);line-height:1.55}.stk-pills[data-astro-cid-fs2v3uau]{display:flex;flex-wrap:wrap;gap:8px;margin-top:14px}.stk-pill-link[data-astro-cid-fs2v3uau]{text-decoration:none}.stk-section[data-astro-cid-fs2v3uau]{margin-bottom:32px}.stk-section-title[data-astro-cid-fs2v3uau]{font-family:var(--f-display);font-size:22px;font-weight:600;letter-spacing:-.02em;color:var(--slate-100);margin:0 0 14px;padding-bottom:10px;border-bottom:1px solid var(--navy-800)}.medical-disclaimer[data-astro-cid-fs2v3uau]{margin-top:12px;font-size:11.5px;color:var(--slate-600)}